What’s on : Cafe-scientifique

A novel microfluidics device to study the impact of 7.00pm mechanical stresses on blood stem cells

Cafe-scientifique
Date
4 Oct 2022
Start time
7:00 PM
Venue
The Guildhall
Speaker
Dr Rasha Rezk, University of York
A novel microfluidics device to study the impact of 7.00pm mechanical stresses on blood stem cells

Event Information

A novel microfluidics device to study the impact of 7.00pm mechanical stresses on blood stem cells

Dr Rasha Rezk, University of York

The first bone marrow transplant was performed in 1956 by Dr E. Donnall Thomas in New York, where diseased stem cells in a patient were replaced by healthy bone marrow from a matched twin sibling. However, not everyone has a matched donor.  To overcome the challenge of finding a suitable donor, scientists have been extensively studying ways to grow healthy stem cells outside the body. Despite our improved understanding of the chemical and molecular modifiers, researchers have yet to identify methods to produce large quantities of highly purified functional stem cells. Tools to explore the biomechanics of HSCs, however, are dramatically lagging and the development of such tools offers the potential to explore mechanical forces as a means to alter cell fate. In York, we have developed a state-of-the-art microfluidic device that allows us to apply compressive forces on blood stem cells to study the impact of physical stress on cells, a property critical for facilitating the scaled-up production of stem cells outside our bodies.

We are meeting in a new venue in the Council Chamber at the Guildhall.   Doors open 7pm.

Talk and Q and A from 7.15pm to 8.15pm

PlEASE PREBOOK BY EVENTBRITE OR CONTACT THE YPS office:

https://www.eventbrite.co.uk/e/york-cafe-scientifique-new-device-in-stem-cell-research-tickets-425926957997